Research
Alpha-gal research tracker
Alpha-gal syndrome research is moving fast. Each week we check PubMed for newly indexed studies and ClinicalTrials.gov for new or updated trials, then write a plain-language roundup of what was published and what it does (and does not) mean for people living with AGS. Every summary links to the original source.
Weekly research roundups
Alpha-gal clinical trials
Studies registered on ClinicalTrials.gov that focus on alpha-gal syndrome or tick-related meat allergy. Last checked October 26, 2026. Talk with your allergist before contacting a study team. Listing a study here is not an endorsement.
Open or opening soon (3)
- RecruitingNCT07177729
The α-gal Syndrome - Investigating Immune Reactions to Tick Bites
An observational study looking at how the immune system responds to tick bites in people with alpha-gal syndrome, to better understand how sensitization develops.
Luxembourg Institute of Health — Started 2025-07-01 — Luxembourg, Luxembourg · Strassen, Luxembourg
- RecruitingNCT07611435Phase 2
Beginning to Assess an Appropriate CONtrol for Oral Food Challenges in Alpha-Gal Syndrome (CoFAR-13) - BeACON4AG
Part of the NIH-funded CoFAR network, this early study is working out what food should be used as a safe comparison during oral food challenges for alpha-gal syndrome.
National Institute of Allergy and Infectious Diseases (NIAID) — Started 2026-09-21 — Little Rock, Arkansas, United States · Chapel Hill, North Carolina, United States · Nashville, Tennessee, United States
- Not yet recruitingNCT07526558Phase 2
Mast Cell Treatment in Post-tick Bite Illness (PTBI)
A planned study of a mast-cell-stabilizing treatment for people with lingering symptoms after a tick bite ('post-tick bite illness'), including some AGS-related presentations.
University of North Carolina, Chapel Hill — Started 2026-04-30 — Chapel Hill, North Carolina, United States
Completed and other studies (3)
- CompletedNCT06268717
GI Alpha-Gal Study
A completed study of gut and digestive symptoms (IBS-like diarrhea, abdominal pain, vomiting) in people with alpha-gal syndrome. Results are not yet posted.
University of North Carolina, Chapel Hill — Started 2023-10-17 — Chapel Hill, North Carolina, United States
- Status unknownNCT04828317
Alpha-gal Pork Challenge
A clinic-based oral challenge study using pork in adults with alpha-gal syndrome. Status is listed as unknown on ClinicalTrials.gov.
University of Virginia — Started 2021-05-01
- CompletedNCT02350660
Oral Immunotherapy for Peanut and Mammalian Meat Allergies
A completed oral immunotherapy study that enrolled people with peanut allergy and with mammalian meat allergy to test gradual, supervised dosing. Results are not yet posted.
University of Virginia — Started 2012-03 — Charlottesville, Virginia, United States
How we put this together
New studies are pulled automatically from the National Library of Medicine's PubMed database and from ClinicalTrials.gov. A draft summary is written from each study's published abstract, then a person on our team reviews every summary against the source before it is published. We summarize abstracts, not full papers, and we say so when a finding is preliminary, small, or from animal or lab work. Spot an error? Tell us. This page is educational and is not medical advice.